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Handbook Of Reagents For Organic Synthesis Reagents For High Throughput Solid Phase And Solution Phase Organic Synthesis

Handbook of Reagents for Organic Synthesis  Reagents for High Throughput Solid Phase and Solution Phase Organic Synthesis PDF

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Author: Jonathan A. Ellman
Publisher: Wiley
ISBN: 9780470862988
Size: 30.34 MB
Format: PDF, Mobi
Category : Science
Languages : en
Pages : 392
View: 755


Since its discovery in 1963 by R. B. Merrifield, solid-phase synthesis, or polymer-supported synthesis, has become an essential technique with its wide use in the synthesis of peptides and other oligomers. Solid-Phase Reactions provides extensive and comprehensive information on this form of synthesis in a format ideal for those working in the laboratory. As part of the Handbook of Reagents in Organic Synthesis Series, this new addition extends the wealth of information available to the chemist at the bench. All content has been expertly collected and presented by an internationally recognised and respected editorial board led by Professor Peter Wipf.

Handbook Of Reagents For Organic Synthesis Reagents For High Throughput Solid Phase And Solution Phase Organic Synthesis

Handbook of Reagents for Organic Synthesis  Reagents for high throughput solid phase and solution phase organic synthesis PDF

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Author:
Publisher:
ISBN:
Size: 79.60 MB
Format: PDF, Kindle
Category : Chemical tests and reagents
Languages : en
Pages :
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Handbook Of Reagents For Organic Synthesis Handbook Of Organic Reagents Set Ii 4 Volume Set

Handbook of Reagents for Organic Synthesis  Handbook of Organic Reagents  Set II  4 Volume Set PDF

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Author: Leo A. Paquette
Publisher: Wiley
ISBN: 9780470066522
Size: 51.38 MB
Format: PDF, Mobi
Category : Science
Languages : en
Pages : 2184
View: 6586


EROS has become a brand name for high quality information on organic reagents. For chemists at the bench we have developed the series of Handbooks of Reagents for Organic Synthesis, which are sold at an attractive price and contain all the necessary information in focused volumes. All content has been expertly collected and presented by an internationally recognised and respected editorial board. Handbook of Organic Reagents: Set II includes the following four volumes: Chiral Reagents for Asymmetric Synthesis, Edited by Prof Leo A. Paquette Reagents for High-Throughput Solid-Phase and Solution-Phase Organic Synthesis, Edited by Peter Wipf Reagents for Glycoside, Nucleotide, and Peptide Synthesis, Edited by David Crich Reagents for Direct Functionalization of C-H Bonds, Edited by Prof Philip L Fuchs Buying the set saves you over 20% on buying the four volumes individually.

Handbook Of Reagents For Organic Synthesis

Handbook of Reagents for Organic Synthesis PDF

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Author: Tomislav Rovis
Publisher: John Wiley & Sons
ISBN: 1119061016
Size: 15.30 MB
Format: PDF, ePub
Category : Science
Languages : en
Pages : 816
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Spurred by the desire to make chemistry a sustainable and "greener" technology, the field of organocatalysis has grown to become one of the most important areas in synthetic organic chemistry. Organic catalysts can often replace potentially toxic metal catalysts and allow reactions to proceed under mild reaction conditions, thereby saving energy costs and rendering chemical processes inherently safer. More importantly perhaps, organocatalysis offers a complementary reactivity in many instances leading to increased versatility.This Handbook describes 126 key reagents for organocatalytic reactions and will be especially useful for professionals in the area of sustainable chemistry, medicinal research, as well as synthetic organic chemists working in academia and the pharmaceutical industry. All the information compiled in this volume is also available in electronic format on Wiley Online Library. The 126 reagents represented here are but a small fraction of the ca. 5,000 reagents available in the electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). e-EROS offers various search interfaces to locate reagents of interest, including chemical structure, substructure and reactions search modes. e-EROS is updated regularly with new and updated entries.

Handbook Of Reagents For Organic Synthesis

Handbook of Reagents for Organic Synthesis PDF

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Author: André B. Charette
Publisher: John Wiley & Sons
ISBN: 1118704886
Size: 11.81 MB
Format: PDF, Docs
Category : Science
Languages : en
Pages : 728
View: 5031


The Handbook is a compilation of 99 articles on diverse reagents and catalysts that describe the synthesis of heteroarenes, the building blocks of a wide range of chemicals used in pharma and chemical industries. Articles are selected from the e-EROS database and edited to make sure that it includes only the material relevant to the topic of the book and focus on the synthetic aspects. This makes the articles very focused on the needs of readers wanting information on specific syntheses of specific heteroarenes. In addition, the chemistry of each parent heteroarene is also included to ensure that the reader rapidly finds important information. The Handbook is a part of the Handbook of Reagents for Organic Chemistry series, aiming at collecting articles on a particular theme that individual researchers in academia or industry can use on a daily basis.

High Throughput Analysis In The Pharmaceutical Industry

High Throughput Analysis in the Pharmaceutical Industry PDF

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Author: Perry G. Wang
Publisher: CRC Press
ISBN: 1420059548
Size: 15.94 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 432
View: 7354


The introduction of combinatorial chemistry technology has increased the amount of compounds generated in a year from 50 to 2000. Conventional analytical approaches simply cannot keep up. These circumstances have caused drug discovery to take on the shape of a bottleneck, like traffic through a toll booth. In order to break the bottleneck, a corres

Reagents For Silicon Mediated Organic Synthesis

Reagents for Silicon Mediated Organic Synthesis PDF

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Author: Philip L. Fuchs
Publisher: John Wiley & Sons
ISBN: 1118636139
Size: 21.79 MB
Format: PDF, Kindle
Category : Technology & Engineering
Languages : en
Pages : 816
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Over the last three decades the importance of organosiliconchemistry has greatly increased because it has opened a number ofnew synthetic strategies. Silicon reagents are usually low-cost,versatile and allow a wide range of reactions. This is the firstHandbook to compile essential Silicon containing reagents and makesuse of the leading reagent database e-EROS. Another hotvolume in the series Handbooks of Reagents for OrganicSynthesis, this is a must-have resource for all syntheticchemists working in drug development and medicinal chemistry. For the selection the Editor focussed on three key syntheticapproaches with the greatest impact: 1. Use of silicon as a 'temporary tether' by unifying a reactivepair of functional groups and taking advantage of theirtemplate-biased intramolecular cyclization. 2. The specific use of the silane functionality as a heterot-butyl group, often colloquially referred to as the use ofsilicon as a 'fat proton'. 3. The use of the Brook rearrangement as an 'anion relaystratagem'. A new feature in this Handbook is the reagent finder, analphabetically organized lookup table arranged by organicfunctionality and specific structure of the silicon atom to whichit is bound.

Reagents For Radical And Radical Ion Chemistry

Reagents for Radical and Radical Ion Chemistry PDF

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Author: David Crich
Publisher: John Wiley & Sons
ISBN: 1118634896
Size: 29.98 MB
Format: PDF, ePub
Category : Science
Languages : en
Pages : 728
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Radicals and radical ions are important intermediates with wide use in organic synthesis. The first book to concentrate on reagents for the creation and use of radicals and radical ions, this new volume in the Handbooks of Reagents for Organic Synthesis series compiles articles taken from the e-eros database, on reagents for use in radical and radical chemistry, to help the chemist in the lab choose the right reagents. Reflecting the enormous growth of radical chemistry over the past ten years, this is an essential guide for all synthetic chemists.

Organosulfur Chemistry In Asymmetric Synthesis

Organosulfur Chemistry in Asymmetric Synthesis PDF

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Author: Takeshi Toru
Publisher: John Wiley & Sons
ISBN: 3527623248
Size: 62.40 MB
Format: PDF
Category : Science
Languages : en
Pages : 448
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In this first book to gather the information on this hot topic otherwise widely spread throughout the literature, experienced editors and top international authors cover everything the reader needs -- from the synthesis of chiral organosulfur compounds to applications and catalysis: * Asymmetric synthesis of chiral sulfinates and sulfoxides * Synthesis and use of chiral dithioacetal derivatives, ylids, chiral sulfoximines and sulfinamides * Use of chiral sulfoxides as ligands in catalysis * Asymmetric reactions of alpha-sulfenyl, alpha-sulfinyl and alpha-sulfonyl carbanions. As a result, readers will be able to improve their own performance in asymmetric synthesis.

Catalyst Components For Coupling Reactions

Catalyst Components for Coupling Reactions PDF

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Author: Gary A. Molander
Publisher: John Wiley & Sons
ISBN: 1118643437
Size: 27.97 MB
Format: PDF, Docs
Category : Science
Languages : en
Pages : 480
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The long awaited Handbook for all synthetic chemists working on coupling reactions, compiling all major catalyst components in use in the area. Consists of a compilation of articles taken from the EROS database, with the inclusion of about 20 newly commissioned catalysts/pre-catalysts/ligands that have made an impact in this area of synthetic organic chemistry. Includes catalyst systems used in Heck, Kumada-Tamao-Corriu, Suzuki-Miyaura, Hiyama-Hatanaka, Negishi, Migita-Kosugi-Stille, Buchwald-Hartwig, and Tsuji-Trost coupling reactions.

High Throughput Synthesis

High Throughput Synthesis PDF

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Author: Irving Sucholeiki
Publisher: CRC Press
ISBN: 9781420056518
Size: 80.57 MB
Format: PDF
Category : Science
Languages : en
Pages : 400
View: 1147


An exploration of high-throughput synthesis, this book presents a compilation of how-to methods, novel materials, and catalyst developments for creating a multitude of new compounds. Introductory sections are coupled with in-depth case studies clarifying theory through practice. The book emphasizes the potential for reproducing experiments in detail.

Combinatorial Chemistry

Combinatorial Chemistry PDF

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Author: Willi Bannwarth
Publisher: John Wiley & Sons
ISBN: 9783527306930
Size: 32.65 MB
Format: PDF, ePub, Docs
Category : Science
Languages : en
Pages : 694
View: 7399


The new edition of this practice-oriented handbook features thoroughly updated contents, including recent developments in parallel synthesis. A new chapter on screening complements the overview of combinatorial strategy and synthetic methods. "Experimental details and complete reaction data [...] are a constant theme running through this work" (Angewandte Chemie) "Recommended to newcomers in the field of combinatorial chemical synthesis because of its broad scope" (Journal of the American Chemical Society)

Reagents For Glycoside Nucleotide And Peptide Synthesis

Reagents for Glycoside  Nucleotide  and Peptide Synthesis PDF

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Author: David Crich
Publisher: Wiley
ISBN: 9780470023044
Size: 27.40 MB
Format: PDF, ePub
Category : Science
Languages : en
Pages : 768
View: 2832


This handbook collects together short, informative articles on approximately 250 of the most widely used reagents in the field, into a single volume. Each of the articles, drawn from the e-EROS database, contains a summary of the most pertinent reactions for every reagent, with references to the original literature. This handbook will have a broad appeal and should find a home in every organic chemistry laboratory and library. Compiles all the essential reagents for syntheses on and with biomolecules Gives key information on protection, bond formation and deprotection An essential resource for all synthetic chemists working in drug development and medicinal chemistry Makes use of the leading reagent database e-EROS

A Handbook For Dna Encoded Chemistry

A Handbook for DNA Encoded Chemistry PDF

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Author: Robert A. Goodnow, Jr.
Publisher: John Wiley & Sons
ISBN: 1118487680
Size: 44.63 MB
Format: PDF, ePub, Mobi
Category : Science
Languages : en
Pages : 480
View: 1027


This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods

Sigma Aldrich Labware

Sigma Aldrich Labware PDF

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Author: Sigma-Aldrich Corporation
Publisher:
ISBN:
Size: 63.96 MB
Format: PDF, Docs
Category : Chemical apparatus
Languages : en
Pages :
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