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Genomes

Genomes PDF

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Author: T. A. Brown
Publisher:
ISBN: 9780815345084
Size: 43.14 MB
Format: PDF, Docs
Category : Science
Languages : en
Pages : 524
View: 2914


Preceded by: Genomes 3 / T. A. Brown. 3rd ed. New York: Garland Science, c2007.

Genomes 4

Genomes 4 PDF

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Author: T. A. Brown
Publisher: Garland Science
ISBN: 1351851284
Size: 45.44 MB
Format: PDF, ePub, Mobi
Category : Science
Languages : en
Pages : 520
View: 3426


Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids. Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important. Each chapter has a set of short-answer questions, in-depth problems, and annotated further reading. There is also an extensive glossary. Genomes 4 is the ideal text for upper level courses focused on genomes and genomics.

Genomes 4

Genomes 4 PDF

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Author: T. A. Brown
Publisher: Garland Science
ISBN: 1351851292
Size: 59.75 MB
Format: PDF, ePub
Category : Science
Languages : en
Pages : 520
View: 2617


Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids. Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important. Each chapter has a set of short-answer questions, in-depth problems, and annotated further reading. There is also an extensive glossary. Genomes 4 is the ideal text for upper level courses focused on genomes and genomics.

Genome Stability

Genome Stability PDF

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Author: Igor Kovalchuk
Publisher: Academic Press
ISBN: 0323856802
Size: 37.95 MB
Format: PDF, ePub
Category : Science
Languages : en
Pages : 760
View: 6322


Genome Stability: From Virus to Human Application, Second Edition, a volume in the Translational Epigenetics series, explores how various species maintain genome stability and genome diversification in response to environmental factors. Here, across thirty-eight chapters, leading researchers provide a deep analysis of genome stability in DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, examining how epigenetic factors contribute to genome stability and how these species pass memories of encounters to progeny. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, and genome stability in response to aging. This second edition has been fully revised to address evolving research trends, including CRISPRs/Cas9 genome editing; conventional versus transgenic genome instability; breeding and genetic diseases associated with abnormal DNA repair; RNA and extrachromosomal DNA; cloning, stem cells, and embryo development; programmed genome instability; and conserved and divergent features of repair. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability. A deep analysis of genome stability research from various kingdoms, including epigenetics and transgenerational effects Provides comprehensive coverage of mechanisms utilized by different organisms to maintain genomic stability Contains applications of genome instability research and outcomes for human disease Features all-new chapters on evolving areas of genome stability research, including CRISPRs/Cas9 genome editing, RNA and extrachromosomal DNA, programmed genome instability, and conserved and divergent features of repair

Biotechnology Volume Iv

BIOTECHNOLOGY   Volume IV PDF

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Author: Horst W. Doelle
Publisher: EOLSS Publications
ISBN: 1848262582
Size: 55.48 MB
Format: PDF, ePub
Category : Biochemical engineering
Languages : en
Pages : 372
View: 1065


This Encyclopedia of Biotechnology is a component of the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. Biotechnology draws on the pure biological sciences (genetics, animal cell culture, molecular biology, microbiology, biochemistry, embryology, cell biology) and in many instances is also dependent on knowledge and methods from outside the sphere of biology (chemical engineering, bioprocess engineering, information technology, biorobotics). This 15-volume set contains several chapters, each of size 5000-30000 words, with perspectives, applications and extensive illustrations. It carries state-of-the-art knowledge in the field and is aimed, by virtue of the several applications, at the following five major target audiences: University and College Students, Educators, Professional Practitioners, Research Personnel and Policy Analysts, Managers, and Decision Makers and NGOs.

Genome Transcriptome And Proteome Analysis

Genome Transcriptome and Proteome Analysis PDF

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Author: Alain Bernot
Publisher: John Wiley and Sons
ISBN: 0470299568
Size: 19.18 MB
Format: PDF, ePub, Mobi
Category : Science
Languages : en
Pages : 248
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Genome Transcriptome and Proteome Analysis is aconcise introduction to the subject, successfully bringing togetherthese three key areas of research. Starting with a revision ofmolecular genetics the book offers clear explanations of the toolsand techniques widely used in genome, transcriptome and proteomeanalysis. Subsequent chapters offer a broad overview of linkagemaps, physical maps and genome sequencing, with a final discussionon the identification of genes responsible for disease. An invaluable introduction to the basic concepts of the subject,this text offers the student an excellent overview of currentresearch methods and applications and is a good starting point forthose new to the area. A clear, concise introduction to the subject of modern genomicanalysis A technology-oriented approach including the latestdevelopments in the field Invaluable to those students taking courses in Bioinformatics,Human Genetics, Biochemistry and Molecular Biology

Comparative Studies On The Structure Of Human Adenovirus Genomes 4 7 And 21

Comparative Studies on the Structure of Human Adenovirus Genomes 4  7 and 21 PDF

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Author: R. K. Padmanabhan
Publisher:
ISBN:
Size: 70.22 MB
Format: PDF, Kindle
Category :
Languages : en
Pages : 32
View: 7406


The overall goal of the project is to study the genomic structure of Adeno virus prototype strains 4, 7 and 21 using several restriction endonucleases and compare their characteristic cleavage maps with those of the corresponding vaccine strains. These three serotypes of adenovirus have been shown to be involved in respiratory diseases among military recruits. Serotype 4 differs from 7 and 21 in that it does not produce tumor in animals, whereas 7 and 21 induce tumors at a moderate frequency. The purpose of the investigation is to develop a non-oncogenic recombinant strain in which the immunogenic region of Ad7 is substituted with the corresponding region from Ad4. The goal is feasible in view of the fact that the oncogenic and immunogenic regions have been shown to reside in different parts of adenovirus genome. A second objective of the project is to develop a plaque for titering the infectivity of Ad4, 7 and 21 vaccine strains in the forms of enteric coated capsules.

Bioinformatics For Geneticists

Bioinformatics for Geneticists PDF

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Author: Michael R. Barnes
Publisher: John Wiley & Sons
ISBN: 0470026197
Size: 32.47 MB
Format: PDF, ePub, Docs
Category : Computers
Languages : en
Pages : 554
View: 1594


Bioinformatics for geneticists describes the key bioinformatics and genetic analysis processes that are needed to identify human genetic determinants. Including SNP functional analysis and statistical genetics.

Epstein Barr Virus Volume 2

Epstein Barr Virus Volume 2 PDF

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Author: Christian Münz
Publisher: Springer
ISBN: 331922834X
Size: 58.20 MB
Format: PDF, ePub
Category : Medical
Languages : en
Pages : 505
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Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.

Norovirus

Norovirus PDF

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Author: Nada M. Melhem
Publisher: Springer Nature
ISBN: 3030272095
Size: 18.58 MB
Format: PDF
Category : Medical
Languages : en
Pages : 251
View: 6200


This book addresses the molecular biology of noroviruses (NoVs), pathogenesis, viral diversity and its impact on selective pressure, host susceptibility and outbreaks, clinical diagnosis, and the latest advances in the management and treatment of disease caused by NoVs. It offers a detailed analysis of our current understanding of the innate and the adaptive immune responses stimulated by NoVs, and discusses the complexity of the ongoing vaccine development and the urgent need for specific immune correlates of protection to advance the field. This is the first book on noroviruses. Written by leading specialists, it is essential reading for virologists and immunologists.

Molecular Biology And Biotechnology Of Plant Organelles

Molecular Biology and Biotechnology of Plant Organelles PDF

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Author: Henry Daniell, Ph.D.
Publisher: Springer Science & Business Media
ISBN: 1402031661
Size: 14.68 MB
Format: PDF, Kindle
Category : Science
Languages : en
Pages : 659
View: 1040


We have taught plant molecular biology and biotechnology at the undergraduate and graduate level for over 20 years. In the past few decades, the field of plant organelle molecular biology and biotechnology has made immense strides. From the green revolution to golden rice, plant organelles have revolutionized agriculture. Given the exponential growth in research, the problem of finding appropriate textbooks for courses in plant biotechnology and molecular biology has become a major challenge. After years of handing out photocopies of various journal articles and reviews scattered through out the print and electronic media, a serendipitous meeting occurred at the 2002 IATPC World Congress held in Orlando, Florida. After my talk and evaluating several posters presented by investigators from my laboratory, Dr. Jacco Flipsen, Publishing Manager of Kluwer Publishers asked me whether I would consider editing a book on Plant Organelles. I accepted this challenge, after months of deliberations, primarily because I was unsuccessful in finding a text book in this area for many years. I signed the contract with Kluwer in March 2003 with a promise to deliver a camera-ready textbook on July 1, 2004. Given the short deadline and the complexity of the task, I quickly realized this task would need a co-editor. Dr. Christine Chase was the first scientist who came to my mind because of her expertise in plant mitochondria, and she readily agreed to work with me on this book.

Fruit Breeding

Fruit Breeding PDF

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Author: Maria Luisa Badenes
Publisher: Springer Science & Business Media
ISBN: 1441907629
Size: 44.91 MB
Format: PDF, Kindle
Category : Science
Languages : en
Pages : 875
View: 913


Fruit Breeding is the eighth volume in the Handbook of Plant Breeding series. Like the other volumes in the series, this volume presents information on the latest scientific information in applied plant breeding using the current advances in the field, from an efficient use of genetic resources to the impact of biotechnology in plant breeding. The majority of the volume showcases individual crops, complemented by sections dealing with important aspects of fruit breeding as trends, marketing and protection of new varieties, health benefits of fruits and new crops in the horizon. The book also features contributions from outstanding scientists for each crop species. Maria Luisa Badenes Instituto Valenciano de Investigaciones Agrarias (IVIA), Valencia, Spain David Byrne Department of Horticultural Sciences, Texas A&M University, College Station, TX, USA

Bioinformatics Algorithms

Bioinformatics Algorithms PDF

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Author: Ion Mandoiu
Publisher: John Wiley & Sons
ISBN: 9780470253427
Size: 49.49 MB
Format: PDF, Docs
Category : Computers
Languages : en
Pages : 520
View: 6804


Presents algorithmic techniques for solving problems in bioinformatics, including applications that shed new light on molecular biology This book introduces algorithmic techniques in bioinformatics, emphasizing their application to solving novel problems in post-genomic molecular biology. Beginning with a thought-provoking discussion on the role of algorithms in twenty-first-century bioinformatics education, Bioinformatics Algorithms covers: General algorithmic techniques, including dynamic programming, graph-theoretical methods, hidden Markov models, the fast Fourier transform, seeding, and approximation algorithms Algorithms and tools for genome and sequence analysis, including formal and approximate models for gene clusters, advanced algorithms for non-overlapping local alignments and genome tilings, multiplex PCR primer set selection, and sequence/network motif finding Microarray design and analysis, including algorithms for microarray physical design, missing value imputation, and meta-analysis of gene expression data Algorithmic issues arising in the analysis of genetic variation across human population, including computational inference of haplotypes from genotype data and disease association search in case/control epidemiologic studies Algorithmic approaches in structural and systems biology, including topological and structural classification in biochemistry, and prediction of protein-protein and domain-domain interactions Each chapter begins with a self-contained introduction to a computational problem; continues with a brief review of the existing literature on the subject and an in-depth description of recent algorithmic and methodological developments; and concludes with a brief experimental study and a discussion of open research challenges. This clear and approachable presentation makes the book appropriate for researchers, practitioners, and graduate students alike.

Genetics Genomics And Breeding Of Eucalypts

Genetics  Genomics and Breeding of Eucalypts PDF

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Author: Robert J. Henry
Publisher: CRC Press
ISBN: 1482254131
Size: 57.36 MB
Format: PDF, Docs
Category : Science
Languages : en
Pages : 206
View: 3444


Eucalypts are used for the production of paper products, firewood, charcoal, potential feedstocks for bioenergy and biomaterials, as ornamentals and landscape trees, and in land rehabilitation. Eucalypt breeding is at an early stage with many plantings being only at the first stages of domestication. The relatively small genomes of these species make the application of molecular genetics approaches attractive. The application of modern genomics will accelerate the development of improved eucalypts for a wide range of uses. This book brings together diverse information on the genetics, genomics, and breeding of these important forest species.

Plant Biotechnology Recent Advancements And Developments

Plant Biotechnology  Recent Advancements and Developments PDF

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Author: Suresh Kumar Gahlawat
Publisher: Springer
ISBN: 9811047324
Size: 79.72 MB
Format: PDF
Category : Science
Languages : en
Pages : 390
View: 3849


This book presents an overview of the latest advances and developments in plant biotechnology. The respective chapters explore emerging areas of plant biotechnology such as RNAi technology, fermentation technology, genetic engineering, nanoparticles and their applications, climate resilient crops, bio-films, bio-plastic, bio-remediation, flavonoids, antioxidants etc. All chapters were written by respected experts and address the latest developments in plant biotechnology that are of industrial importance, especially with regard to crop yields and post-harvest strategies. As such, the book offers a valuable guide for students, educators and researchers in all disciplines of the life sciences, agricultural sciences, medicine, and biotechnology at universities, research institutions and biotechnology companies.

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