Automated Reasoning For Systems Biology And Medicine

Automated Reasoning for Systems Biology and Medicine PDF Book Detail:
Author: Pietro Liò
Publisher: Springer
ISBN: 303017297X
Size: 59.44 MB
Format: PDF, Docs
Category : Computers
Languages : en
Pages : 474
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Book Description: This book presents outstanding contributions in an exciting, new and multidisciplinary research area: the application of formal, automated reasoning techniques to analyse complex models in systems biology and systems medicine. Automated reasoning is a field of computer science devoted to the development of algorithms that yield trustworthy answers, providing a basis of sound logical reasoning. For example, in the semiconductor industry formal verification is instrumental to ensuring that chip designs are free of defects (or “bugs”). Over the past 15 years, systems biology and systems medicine have been introduced in an attempt to understand the enormous complexity of life from a computational point of view. This has generated a wealth of new knowledge in the form of computational models, whose staggering complexity makes manual analysis methods infeasible. Sound, trusted, and automated means of analysing the models are thus required in order to be able to trust their conclusions. Above all, this is crucial to engineering safe biomedical devices and to reducing our reliance on wet-lab experiments and clinical trials, which will in turn produce lower economic and societal costs. Some examples of the questions addressed here include: Can we automatically adjust medications for patients with multiple chronic conditions? Can we verify that an artificial pancreas system delivers insulin in a way that ensures Type 1 diabetic patients never suffer from hyperglycaemia or hypoglycaemia? And lastly, can we predict what kind of mutations a cancer cell is likely to undergo? This book brings together leading researchers from a number of highly interdisciplinary areas, including: · Parameter inference from time series · Model selection · Network structure identification · Machine learning · Systems medicine · Hypothesis generation from experimental data · Systems biology, systems medicine, and digital pathology · Verification of biomedical devices “This book presents a comprehensive spectrum of model-focused analysis techniques for biological systems ...an essential resource for tracking the developments of a fast moving field that promises to revolutionize biology and medicine by the automated analysis of models and data.”Prof Luca Cardelli FRS, University of Oxford

Advances In Multidisciplinary Medical Technologies Engineering Modeling And Findings

Advances in Multidisciplinary Medical Technologies     Engineering  Modeling and Findings PDF Book Detail:
Author: Abdeldjalil Khelassi
Publisher: Springer Nature
ISBN: 3030575527
Size: 11.11 MB
Format: PDF, ePub, Mobi
Category : Technology & Engineering
Languages : en
Pages : 270
View: 4566

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Book Description: This book collects the proceedings of the International Congress on Health Sciences and Medical Technologies (ICHSMT), held in Tlemcen, Algeria, from December 5 to 7, 2019. The proceedings present a forum for the latest projects and research in scientific and technological development with an emphasis on smart healthcare system design and future technologies. ICHSMT brings together researchers, students, and professionals from the healthcare, corporate, and academic sectors. It includes a far-reaching program supported by a variety of technical tracks that seek to promote medical technologies and innovation at a nationwide level.

Verifying Cyber Physical Systems

Verifying Cyber Physical Systems PDF Book Detail:
Author: Sayan Mitra
Publisher:
ISBN: 0262044803
Size: 63.26 MB
Format: PDF, Kindle
Category : Cooperating objects (Computer systems)
Languages : en
Pages : 312
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Book Description: "A unified mathematical framework for rigorously modeling and analyzing cyber-physical systems"--

Multi Agent Systems

Multi Agent Systems PDF Book Detail:
Author: Ariel Rosenfeld
Publisher: Springer Nature
ISBN: 3030822540
Size: 18.16 MB
Format: PDF, Mobi
Category :
Languages : en
Pages :
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Book Description:

Computer Aided Verification

Computer Aided Verification PDF Book Detail:
Author: Isil Dillig
Publisher: Springer
ISBN: 3030255409
Size: 16.33 MB
Format: PDF, ePub, Mobi
Category : Artificial intelligence
Languages : en
Pages : 673
View: 7236

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Book Description: The open access two-volume set LNCS 11561 and 11562 constitutes the refereed proceedings of the 31st International Conference on Computer Aided Verification, CAV 2019, held in New York City, USA, in July 2019. The 52 full papers presented together with 13 tool papers and 2 case studies, were carefully reviewed and selected from 258 submissions. The papers were organized in the following topical sections: Part I: automata and timed systems; security and hyperproperties; synthesis; model checking; cyber-physical systems and machine learning; probabilistic systems, runtime techniques; dynamical, hybrid, and reactive systems; Part II: logics, decision procedures; and solvers; numerical programs; verification; distributed systems and networks; verification and invariants; and concurrency.

Integrated Formal Methods

Integrated Formal Methods PDF Book Detail:
Author: Wolfgang Ahrendt
Publisher: Springer Nature
ISBN: 3030349683
Size: 19.28 MB
Format: PDF, Docs
Category : Computers
Languages : en
Pages : 554
View: 6776

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Book Description: This book constitutes the refereed proceedings of the 15th International Conference on Integrated Formal Methods, IFM 2019, held in Bergen, Norway, in December 2019. The 25 full papers and 3 short papers were carefully reviewed and selected from 95 submissions. The papers cover a broad spectrum of topics: from language design to verification and analysis techniques, to supporting tools and their integration into software engineering practice including both theoretical approaches and practical implementations. Also included are the extended abstracts of 6 "journal-first" papers.

Cancer Systems Biology Bioinformatics And Medicine

Cancer Systems Biology  Bioinformatics and Medicine PDF Book Detail:
Author: Alfredo Cesario
Publisher: Springer Science & Business Media
ISBN: 9789400715677
Size: 54.98 MB
Format: PDF, ePub
Category : Medical
Languages : en
Pages : 484
View: 6483

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Book Description: This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods. Specifically, the book: 1) Sets the stage by describing the basis of systems biology and bioinformatics approaches, and the clinical background of cancer in a systems context; 2) Summarizes the laboratory, clinical, data systems analysis and bioinformatics tools, along with infrastructure and resources required; 3) Demonstrates the application of these tools to cancer research; 4) Extends these tools and methods to clinical diagnosis, drug development and treatment applications; and 5) Finishes by exploring longer term perspectives and providing conclusions. This book reviews the state-of-the-art, and goes beyond into new applications. It is written and highly referenced as a textbook and practical guide aimed at students, academics, doctors, clinicians, industrialists and managers in cancer research and therapeutic applications. Ideally, it will set the stage for integration of available knowledge to optimize communication between basic and clinical researchers involved in the ultimate fight against cancer, whatever the field of specific interest, whatever the area of activity within translational research.